Endace-160 Tablet contains Megestrol, a Progestogen. Megestrol may work by affecting certain hormones. This may increase appetite, helping with weight loss. Endace-160 Tablet is used as a symptomatic treatment in patients with breast cancer and endometrial cancer. Breast cancer develops in the breast cells and is characterised by a lump in the breast, a change in the shape of the nipple or breast, and bloody discharge from the nipples.