Leading Wormisect 444 (fenbendazole ), Supplier from INDIA to Washington, USA | City Drug Exporters
City Drug Exporters supplies Wormisect 444 (fenbendazole ) from INDIA to Washington, USA. Trusted pharmaceutical exporter for wholesalers, distributors, pharmacies, and healthcare procurement companies
Wormisect 444 (fenbendazole ), a broad-spectrum benzimidazole anthelmintic medication. It acts as a microtubule-destabilizing agent that binds to parasite tubulin, disrupting energy metabolism and eventually starving the targeted helminth.
Mechanism of Action :
Fenbendazole irreversibly binds to the β-tubulin of parasites.
It prevents the polymerization of tubulin into microtubules.
This disrupts vital cellular structures and glucose uptake.
The parasite is immobilized, starves, and is eventually killed.
Both adult worms and developing larvae are impacted.
Spectrum of Activity :
It targets a wide variety of gastrointestinal parasites.
Effective against: Roundworms, hookworms, whipworms, and pinworms.
Effective against: Giardia and certain tapeworms (e.g., Taenia)
Pharmacokinetics
Absorption: It features very poor oral absorption in the gastrointestinal tract. This limited absorption is actually advantageous, as it keeps the drug highly localized in the gut where the parasites reside.
Metabolism: A small amount that is absorbed is rapidly metabolized by the liver into active metabolites (like oxfendazole).
Excretion: The unabsorbed drug and metabolites are primarily excreted in the feces.
