City Drug House Exporters | Hepatitis Medicines Supplier to Washington, USA
City Drug House Exporters supplies and exports high-quality hepatitis medicines from India to Washington, USA with trusted pharma solutions and timely global delivery.
Velpanat is a fixed-dose combination antiviral medication containing sofosbuvir (400 mg) and velpatasvir (100 mg). It is prescribed for the treatment of chronic Hepatitis C Virus (HCV) infection across all six major genotypes. The drug achieves a viral cure rate exceeding 90% by halting viral replication directly in the liver.
Mechanism of Action : The two active ingredients target the Hepatitis C virus at distinct stages of its replication cycle:
Sofosbuvir: Acts as a nucleotide analog inhibitor of the HCV NS5B RNA-dependent RNA polymerase. Once inside the body, it is metabolized into its active form and gets incorporated into the viral RNA chain, acting as a chain terminator to prevent viral genome synthesis.
Velpatasvir: Acts as a direct-acting pan-genotypic inhibitor of the HCV NS5A protein. This protein is essential for both viral replication and the assembly of new viral particles. By binding to NS5A, velpatasvir prevents these processes from occurring.
Pharmacokinetics :
Administration: Taken orally, usually as one tablet daily with or without food.
Absorption & Metabolism: Both drugs are rapidly absorbed in the gastrointestinal tract. Sofosbuvir is extensively metabolized into its active form, while velpatasvir undergoes minor metabolism via the liver's CYP enzymes (CYP2B6, CYP2C8, and CYP3A4).
Excretion: Sofosbuvir and its active metabolite are primarily excreted by the kidneys (approx 80%). Velpatasvir is excreted mostly via the feces (approx 94%) and minimally in the urine.
City Drug House Exporters provides:
Bulk supply for hospitals & distributors
Export to USA. Washington, INDIA
Regulatory documents (COA, MSDS, etc.)
Competitive pricing & reliable logistics
Contact for More Information :
📞 Contact City drug House Exporters from India
🌐 Websites:
https://www.citydrugexporters.com
📧 Email: citydrug123@gmail.com
📦 Business Type: Exporter | Bulk Supplier | Distributor
📲 WhatsApp: +91 9975390171
