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Tenvir 300 (Tenofovir Disoproxil Fumarate )

City Drug House Exporters | Hepatitis Medicines Supplier to Washington, USA City Drug House Exporters supplies and exports high-quality hepatitis medicines from India to Washington, USA with trusted pharma solutions and timely global delivery. Tenvir 300 contains Tenofovir Disoproxil Fumarate (300 mg), an antiviral medication used to treat chronic Hepatitis B and manage HIV-1 infections. It works by inhibiting essential viral enzymes—reverse transcriptase in HIV and DNA polymerase in HBV—stopping the virus from multiplying in human cells. Drug Class & Mechanism Drug Class: Nucleotide analog reverse transcriptase inhibitor (NtRTI). Action: Taken as a prodrug, it is rapidly converted to its active form, tenofovir diphosphate, inside cells. It blocks viral replication by inserting itself into the viral DNA chain, which causes immediate chain termination. Pharmacokinetics Metabolism: Primarily intracellular; it bypasses the liver's CYP450 enzyme system, meaning it has a lower risk of certain drug interactions. Excretion: Primarily excreted unchanged in the urine via the kidneys Half-life: The intracellular half-life is approximately 10 to 50 hours, permitting once-daily dosing. Indications & Dosage Standard Adult Dose: 300 mg taken orally once daily.HIV: Must always be combined with other antiretroviral (ARV) drugs. Hepatitis B: Can be used as a standalone monotherapy. Post-Exposure Prophylaxis (PEP): Often used for 28 days following potential occupational or non-occupational exposure to HIV. Important Considerations Kidney Function: Because the drug is cleared through the kidneys, patients with pre-existing renal issues may need dose adjustments. Bone Health: Long-term use has been associated with a decrease in bone mineral density. Lactic Acidosis: Rare but severe cases of lactic acidosis and hepatomegaly (enlarged liver) have been reported. Not a Cure: It does not cure HIV or Hepatitis B, but it reduces the viral load in the blood to undetectable levels, protecting the immune system and liver. City Drug House Exporters provides: Bulk supply for hospitals & distributors Export to USA. Washington, INDIA Regulatory documents (COA, MSDS, etc.) Competitive pricing & reliable logistics Contact for More Information : 📞 Contact City drug House Exporters from India 🌐 Websites: https://www.citydrugexporters.com 📧 Email: citydrug123@gmail.com 📦 Business Type: Exporter | Bulk Supplier | Distributor 📲 WhatsApp: +91 9975390171
 2026-05-19T08:30:06

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