City Drug House Exporters | Hepatitis Medicines Supplier to Washington, USA, INDIA
City Drug House Exporters supplies and exports high-quality hepatitis medicines from India to Washington, USA with trusted pharma solutions and timely global delivery.
SOFOCURE is a direct-acting antiviral medication primarily used to treat chronic Hepatitis C virus (HCV) infections. Depending on the specific formulation, it typically contains the active pharmaceutical ingredient Sofosbuvir alone or in a fixed-dose combination with other antivirals like Velpatasvir to cure the infection and prevent liver damage.
Mechanism of Action
Sofosbuvir: Acts as a nucleotide analog polymerase inhibitor. It is metabolized into an active form that inserts itself into the viral RNA chain, blocking the NS5B RNA-dependent RNA polymerase enzyme. This stops the virus from multiplying, essentially acting as a 'chain terminator'.
Velpatasvir (if combined): Targets and inhibits the NS5A protein, which is another crucial enzyme required for viral replication and assembly.
Pharmacokinetics
Bioavailability: Rapidly absorbed and reaches peak plasma concentration within 0.5 to 2 hours of oral administration. It can typically be taken with or without food.
Metabolism: Primarily metabolized in the liver to form the active pharmacologic agent (GS-461203).
Half-Life: The active metabolite has a terminal half-life of roughly 27 hours, supporting once-daily oral dosing.
Excretion: Mostly eliminated through urine (about 80%), with a smaller fraction excreted via feces.
Indications :
Indicated for adults (and children aged 3 and older) with chronic HCV across multiple viral genotypes.
Frequently used in patients preparing for a liver transplant to prevent recurrence of the virus post-surgery.
City Drug House Exporters provides:
Bulk supply for hospitals & distributors
Export to USA. Washington, INDIA
Regulatory documents (COA, MSDS, etc.)
Competitive pricing & reliable logistics
Contact for More Information :
📞 Contact City drug House Exporters from India
🌐 Websites:
https://www.citydrugexporters.com
📧 Email: citydrug123@gmail.com
📦 Business Type: Exporter | Bulk Supplier | Distributor
📲 WhatsApp: +91 9975390171
