Exporter India Pomalid 4 Mg Capsules(Pomalidomide)| Bulk Supply Oncology Drugs .
Buy Pomalid 4 Mg Capsules(Pomalidomide) in bulk from India. Leading oncology drug exporter City Drug House Exporters offering global supply with latest regulatory updates and competitive pricing.
Mechanism of Action :
Targeted Destruction: Acts as a cereblon E3 ubiquitin ligase complex modulator, leading to ubiquitination and degradation of specific transcription factors (IKZF1/3) essential for myeloma cell survival.
Immunomodulation: Stimulates T-cell and NK cell-mediated immunity; decreases proinflammatory cytokines (TNF-alfa, IL-6).
Anti-angiogenic: Inhibits new blood vessel formation necessary for tumor growth.
Apoptosis & Cycle Arrest: Induces direct apoptosis and arrests cell cycle at G1 phase.
Indications & Usage :
Multiple Myeloma (MM): Used in combination with dexamethasone for relapsed/refractory patients who have received at least two prior therapies, including lenalidomide and a proteasome inhibitor, and have progressed within 60 days of their last treatment.
Kaposi Sarcoma (KS): Treats AIDS-related KS after HAART failure or HIV-negative KS.
Dosage: Generally 4 mg orally once daily on Days 1-21 of repeated 28-day cycles.
Pharmacokinetics (What the body does)
Absorption: Rapidly absorbed;
(time to peak) is 2-3 hours.
Bioavailability: ~73%.
Metabolism: Primarily hepatic via CYP1A2 and CYP3A4.
Elimination: 73% urine, 15% feces; Half-life (t1/2) is approx. 7.5–9.5 hours.
City Drug House Exporters provides:
Bulk supply for hospitals & distributors
Export to USA. Washington, INDIA
Regulatory documents (COA, MSDS, etc.)
Competitive pricing & reliable logistics
Contact for More Information :
📞 Contact City drug House Exporters from India
🌐 Websites: https://www.citydrugexporters.com
📧 Email: citydrug123@gmail.com
📦 Business Type: Exporter | Bulk Supplier | Distributor
📲 WhatsApp: +91 9975390171
