Exporter India Pomalid 2 Mg Capsules(Pomalidomide)| Bulk Supply Oncology Drugs .
Buy Pomalid 2 Mg Capsules(Pomalidomide) in bulk from India. Leading oncology drug exporter City Drug House Exporters offering global supply with latest regulatory updates and competitive pricing.
Pharmacology Tags & Key Characteristics :
Drug Class: Immunomodulatory Agent (IMiD), Thalidomide Analog.
Mechanism of Action: E3 ubiquitin ligase complex inhibitor (targets Cereblon), anti-angiogenic, induces tumor cell apoptosis.
Indication: Multiple Myeloma (third-line), AIDS-related Kaposi sarcoma.
Administration: Oral (capsule).
Metabolism: Primarily Hepatic (CYP1A2 and CYP3A4).
Elimination: Urine (73%), Feces (15%).
Half-Life: App 7.5 Hrs
hours.
Boxed Warning: Embryo-fetal toxicity (teratogenic), Venous/Arterial Thromboembolism.
Key Pharmacological Actions
Immunomodulation: Enhances T-cell and Natural Killer (NK) cell-mediated immunity.
Anti-angiogenesis: Inhibits the formation of new blood vessels, starving tumors.
Antineoplastic: Induces cell cycle arrest and apoptosis (cell death) in myeloma cells.
Pharmacokinetics (PK)
Absorption: Rapidly absorbed, with a peak plasma concentration (Tmax) of 2–3 hours.
Bioavailability: At least 73%.
Protein Binding: 12%–44%
Significant Warnings
Teratogenicity: Causes severe birth defects; strict contraception is required.
Hematologic Toxicity: Can cause severe neutropenia and thrombocytopenia.
Hepatic Risk: Monitor for liver failure.
Common Side Effects :
Fatigue/weakness
Neutropenia (low white blood cells)
Anemia
Constipation, nausea, diarrhea
Peripheral neuropathy (numbness/tingling)
City Drug House Exporters provides: Bulk supply for hospitals & distributors Export to USA. Washington, INDIA Regulatory documents (COA, MSDS, etc.) Competitive pricing & reliable logistics
Contact for More Information :
📞 Contact City drug House Exporters from India
🌐 Websites: https://www.citydrugexporters.com
📧 Email: citydrug123@gmail.com
📦 Business Type: Exporter | Bulk Supplier | Distributor
📲 WhatsApp: +91 9975390171
