Exporter India Pomalid 1 Mg Capsules(Pomalidomide)| Bulk Supply Oncology Drugs .
Buy Pomalid 1 Mg Capsules(Pomalidomide) in bulk from India. Leading oncology drug exporter City Drug House Exporters offering global supply with latest regulatory updates and competitive pricing.
Mechanism of Action (MOA) Pomalidomide acts through several pathways:
1.Direct Anti-myeloma: Binds to the protein cereblon (CRBN), leading to the ubiquitination and degradation of transcription factors Aiolos (IKZF3) and Ikaros (IKZF1), which are crucial for myeloma cell survival.
2.Immunomodulation: Increases T-cell and natural killer (NK) cell proliferation, and inhibits pro-inflammatory cytokines (like TNF- alfa).
3.Anti-angiogenesis: Inhibits the formation of new blood vessels, restricting tumor growth.
Pharmacokinetics
1.Bioavailability: 73% (at least).
2.Absorption: Rapidly absorbed, with peak plasma levels occurring within 2–3 hours.
3.Metabolism: Primarily hepatic via CYP1A2 and CYP3A4. 4.Elimination Half-life: Approximately 7.5 hours. 5.Excretion: Mostly urine (73%) and feces (15%).
City Drug House Exporters provides: Bulk supply for hospitals & distributors Export to USA. Washington, INDIA Regulatory documents (COA, MSDS, etc.) Competitive pricing & reliable logistics
Contact for More Information :
📞 Contact City drug House Exporters from India
🌐 Websites: https://www.citydrugexporters.com
📧 Email: citydrug123@gmail.com
📦 Business Type: Exporter | Bulk Supplier | Distributor
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