Leading Nitrocan 25 Injection ( Nitroglycerin) Supplier from INDIA to Washington, USA | City Drug Exporters
City Drug Exporters supplies Nitrocan 25 Injection ( Nitroglycerin) from INDIA to Washington, USA. Trusted pharmaceutical exporter for wholesalers, distributors, pharmacies, and healthcare procurement companies
Nitrocan 25 Injection contains Nitroglycerin (Glyceryl Trinitrate), an intravenous vasodilator. It treats angina pectoris (chest pain), controls perioperative blood pressure, and manages acute heart failure by relaxing blood vessels and reducing the heart's workload.
Mechanism of Action :
Nitric Oxide (NO) release: The drug converts into NO in vascular smooth muscle cells.
Enzyme activation: NO activates guanylate cyclase, increasing intracellular cGMP.
Vascular relaxation: Increased cGMP leads to dephosphorylation of myosin, relaxing smooth muscle.
Venodilation: Systemic vasodilation reduces preload (blood returning to the heart).
Arteriodilation: At higher doses, arterial dilation decreases afterload (resistance against the heart)
Pharmacokinetics :
Onset of Action: Immediate, typically within 1 to 3 minutes of administration.
Duration of Action: Very short-lived, lasting only about 3 to 5 minutes after stopping the infusion.
Metabolism: Rapidly metabolized in the liver and red blood cells by nitrate reductases.
Half-Life: Approximately 1 to 3 minutes.
Excretion: Metabolites are excreted primarily via the urine
City Drug House Exporters provides:
Bulk supply for hospitals & distributors
Export to USA. Washington, INDIA
Regulatory documents (COA, MSDS, etc.)
Competitive pricing & reliable logistics
Contact for More Information :
📞 Contact City drug House Exporters from India
🌐 Websites:
https://www.citydrugexporters.com
📧 Email: citydrug123@gmail.com
📦 Business Type: Exporter | Bulk Supplier | Distributor
📲 WhatsApp: +91 9975390171
