Leading Milrican 10 Injection (Milrinone lactate) , Supplier from INDIA to Washington, USA | City Drug Exporters
City Drug Exporters supplies Milrican 10 Injection (Milrinone lactate) , from INDIA to Washington, USA. Trusted pharmaceutical exporter for wholesalers, distributors, pharmacies, and healthcare procurement companies
Milrican 10 Injection (Milrinone lactate) , a selective phosphodiesterase 3 (PDE-3) inhibitor primarily used for the short-term intravenous treatment of acute decompensated heart failure. Classified as an inodilator, it improves heart function by increasing myocardial contractility (pumping strength) and promoting vasodilation (widening blood vessels to reduce workload).
Mechanism of Action :
PDE-3 Inhibition: Blocks the PDE-3 enzyme inside cardiac and vascular smooth muscle cells.
cAMP Accumulation: Prevents the breakdown of cyclic AMP (cAMP).
Calcium Influx: Elevates intracellular cAMP to increase calcium influx into cardiac cells, strengthening contractions.
Smooth Muscle Relaxation: Dilates arteries and veins, decreasing systemic vascular resistance and pulmonary capillary wedge pressure.
Pharmacokinetics :
Route of Administration: Intravenous (IV) infusion only.
Onset of Action: 5 to 15 minutes.
Half-Life: Approximately 2.3 hours.
Metabolism: Primarily excreted renally as the unchanged drug.
Warnings & Side Effects :
Arrhythmia Risk: Increased risk of life-threatening ventricular arrhythmias (e.g., ventricular tachycardia).
Hypotension: May cause a dangerous drop in blood pressure due to vasodilation.
Monitoring: Requires continuous electrocardiographic (ECG) monitoring in a hospital setting.
City Drug House Exporters provides:
Bulk supply for hospitals & distributors
Export to USA. Washington, INDIA
Regulatory documents (COA, MSDS, etc.)
Competitive pricing & reliable logistics
Contact for More Information :
📞 Contact City drug House Exporters from India
🌐 Websites:
https://www.citydrugexporters.com
📧 Email: citydrug123@gmail.com
📦 Business Type: Exporter | Bulk Supplier | Distributor
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