Leading Lignocaine Injection Supplier from INDIA to Washington, USA | City Drug Exporters
City Drug Exporters supplies Lignocaine Injection from INDIA to Washington, USA. Trusted pharmaceutical exporter for wholesalers, distributors, pharmacies, and healthcare procurement companies
Lignocaine (also known as lidocaine) is an amide-type local anesthetic and Class Ib antiarrhythmic. By blocking voltage-gated sodium channels, it prevents nerve impulse generation and conduction. It provides rapid, localized pain relief and regulates abnormal heart rhythms.
Mechanism of Action :
Local Anesthesia: Diffuses into nerves, un-ionizes, and blocks voltage-gated sodium channels from the inside.
Pain Blockade: Inhibits the ionic fluxes required for depolarization.
Antiarrhythmic: Stabilizes cardiac cell membranes and reduces ventricular automaticity
.Anti-inflammatory: Possesses immuno-modulating and antinociceptive properties.
Onset: Rapid, taking effect within 45 to 90 seconds (IV) or 2 to 5 minutes (infiltration).
Duration: Lasts 1 to 2 hours, which can be doubled by adding epinephrine.
Distribution: Highly bound to alpha-1-acid glycoprotein in the blood; crosses the blood-brain barrier easily.
Metabolism: Extensively metabolized in the liver (via CYP3A4) into active metabolites, notably MEGX.
Excretion: Metabolites and unchanged drug are excreted by the kidneys.
Administration and Dosage :
Standard Dosing: The maximum safe dose without epinephrine is 5 mg/kg.
With Epinephrine: The maximum safe dose increases to 7 mg/kg.
Max Total Dose: Generally capped at 300 mg to 500 mg depending on the concentration.
Routes: Administered via infiltration, nerve block, epidural, or intravenous (IV).
City Drug House Exporters provides:
Bulk supply for hospitals & distributors
Export to USA. Washington, INDIA
Regulatory documents (COA, MSDS, etc.)
Competitive pricing & reliable logistics
Contact for More Information :
📞 Contact City drug House Exporters from India
🌐 Websites:
https://www.citydrugexporters.com
📧 Email: citydrug123@gmail.com
📦 Business Type: Exporter | Bulk Supplier | Distributor
📲 WhatsApp: +91 9975390171
