Leading Magnesium chloride injection Supplier from INDIA to Washington, USA | City Drug Exporters
City Drug Exporters supplies L-Magnesium chloride injection from INDIA to Washington, USA. Trusted pharmaceutical exporter for wholesalers, distributors, pharmacies, and healthcare procurement companies
Magnesium chloride injection is a sterile, concentrated solution (typically 200 mg/mL) used as an electrolyte replenisher. It is administered by healthcare professionals to treat or prevent severe magnesium deficiencies and to provide magnesium for patients receiving total parenteral nutrition (TPN).
Mechanism of Action :
Enzymatic Cofactor: Magnesium ions act as essential cofactors for over 300 enzymatic reactions, including those vital for DNA/RNA synthesis, ATP utilization, and glucose metabolism.
Neuromuscular Excitability: It regulates neuromuscular transmission and muscle contraction by decreasing acetylcholine release at the motor end-plate and slowing the rate of SA node impulses.
Pharmacokinetics :
Onset & Duration: Intravenous (IV) or intramuscular (IM) administration produces an immediate pharmacological effect, with action lasting roughly 30 minutes to hours.
Distribution: Magnesium is the second most abundant intracellular cation. It distributes widely into body fluids, with roughly 30% bound to proteins.
Metabolism & Excretion: It is not significantly metabolized in the liver. Elimination is almost exclusively renal. The kidneys regulate serum levels by filtering and reabsorbing the ion depending on the body's needs.
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