Leading Linezolid 600 mg injection Supplier from INDIA to Washington, USA | City Drug Exporters
City Drug Exporters supplies Linezolid 600 mg injection from INDIA to Washington, USA. Trusted pharmaceutical exporter for wholesalers, distributors, pharmacies, and healthcare procurement companies
Linezolid 600 mg injection is an oxazolidinone antibiotic. It treats severe, multi-drug resistant Gram-positive bacterial infections, including pneumonia and complicated skin infections. It works by halting bacterial protein synthesis. It achieves this by binding to the 23S ribosomal RNA of the 50S subunit.
Mechanism of Action
Class: Synthetic oxazolidinone antimicrobial.
Binding Site: 23S ribosomal RNA of the 50S subunit.
Inhibition: Blocks the 70S initiation complex.
Effect: Arrests bacterial protein translation.
Activity: Primarily bacteriostatic.
Pharmacokinetics (PK) :
Bioavailability: Nearly 100%.
Distribution: Highly to well-perfused tissues (lungs, skin, CNS).
Protein Binding: Approximately 31%.
Metabolism: Hepatic, via non-enzymatic oxidation.
CYP450: Does not interact with the cytochrome system.
Half-Life: 4 to 5 hours.
Excretion: Via kidneys (primarily as metabolites) and feces.
Spectrum of Activity :
Gram-Positive: MRSA, VRE, and Staphylococci.
Effectiveness: Bactericidal against Streptococci.
Gram-Negative: Not effective.
Precautions and Warnings
Blood Dyscrasias: Risk of thrombocytopenia and anemia with prolonged use.
Lab Monitoring: Requires weekly complete blood counts (CBC).
Neurological: Risk of peripheral and optic neuropathy.
Serotonin Syndrome: Interacts with serotonergic psychiatric drugs.
Dietary: Avoid high-tyramine foods to prevent hypertensive crisis.
City Drug House Exporters provides:
Bulk supply for hospitals & distributors
Export to USA. Washington, INDIA
Regulatory documents (COA, MSDS, etc.)
Competitive pricing & reliable logistics
Contact for More Information :
📞 Contact City drug House Exporters from India
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https://www.citydrugexporters.com
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📦 Business Type: Exporter | Bulk Supplier | Distributor
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