City Drug House Exporters | Hepatitis Medicines Supplier to Washington, USA, INDIA
City Drug House Exporters supplies and exports high-quality hepatitis medicines from India to Washington, USA with trusted pharma solutions and timely global delivery.
Ledikast 90/400 is a fixed-dose combination antiviral medication containing Ledipasvir (90 mg) and Sofosbuvir (400 mg). It is primarily used to treat chronic Hepatitis C virus (HCV) infections, particularly in genotypes 1, 4, 5, and 6.
Mechanism of Action (How it Works)
Ledikast combines two direct-acting antivirals (DAAs) that attack the Hepatitis C virus at different stages of its lifecycle, preventing it from multiplying and allowing the immune system to clear the virus:
Ledipasvir: Functions as an NS5A inhibitor. It targets and inhibits the NS5A protein, which is essential for both viral replication and the assembly of the virus.
Sofosbuvir: Acts as a nucleotide analog NS5B polymerase inhibitor. It integrates into the RNA of the virus and stops the enzyme responsible for copying the virus’s genetic material.
Pharmacokinetics & Dosing :
Dosing: The standard adult dose is one tablet taken orally, once a day, with or without food.
Absorption: Ledipasvir reaches its median peak concentration around 4 to 4.5 hours after administration. Sofosbuvir is absorbed rapidly, with peak plasma levels occurring in about 0.8 to 1 hour.
Duration: Treatment length generally ranges from 8 to 12 weeks, depending on the HCV genotype, prior treatment history, and whether the patient has liver cirrhosis.
Important Safety Considerations
Hepatitis B: It is generally not recommended for patients with a known history of active Hepatitis B infection, as there is a risk of reactivation.
Common Side Effects: The most frequent side effects reported during treatment include fatigue, headache, and mild nausea.
Drug Interactions: This medication can interact with several other drugs (e.g., amiodarone for heart rhythms, or rifampin). Always provide your healthcare provider with a full list of your current medications.
City Drug House Exporters provides:
Bulk supply for hospitals & distributors
Export to USA. Washington, INDIA
Regulatory documents (COA, MSDS, etc.)
Competitive pricing & reliable logistics
Contact for More Information :
📞 Contact City drug House Exporters from India
🌐 Websites:
https://www.citydrugexporters.com
📧 Email: citydrug123@gmail.com
📦 Business Type: Exporter | Bulk Supplier | Distributor
📲 WhatsApp: +91 9975390171
City Drug House Exporters supplies and exports high-quality hepatitis medicines from India to Washington, USA with trusted pharma solutions and timely global delivery.
Ledikast 90/400 is a fixed-dose combination antiviral medication containing Ledipasvir (90 mg) and Sofosbuvir (400 mg). It is primarily used to treat chronic Hepatitis C virus (HCV) infections, particularly in genotypes 1, 4, 5, and 6.
Mechanism of Action (How it Works)
Ledikast combines two direct-acting antivirals (DAAs) that attack the Hepatitis C virus at different stages of its lifecycle, preventing it from multiplying and allowing the immune system to clear the virus:
Ledipasvir: Functions as an NS5A inhibitor. It targets and inhibits the NS5A protein, which is essential for both viral replication and the assembly of the virus.
Sofosbuvir: Acts as a nucleotide analog NS5B polymerase inhibitor. It integrates into the RNA of the virus and stops the enzyme responsible for copying the virus’s genetic material.
Pharmacokinetics & Dosing :
Dosing: The standard adult dose is one tablet taken orally, once a day, with or without food.
Absorption: Ledipasvir reaches its median peak concentration around 4 to 4.5 hours after administration. Sofosbuvir is absorbed rapidly, with peak plasma levels occurring in about 0.8 to 1 hour.
Duration: Treatment length generally ranges from 8 to 12 weeks, depending on the HCV genotype, prior treatment history, and whether the patient has liver cirrhosis.
Important Safety Considerations
Hepatitis B: It is generally not recommended for patients with a known history of active Hepatitis B infection, as there is a risk of reactivation.
Common Side Effects: The most frequent side effects reported during treatment include fatigue, headache, and mild nausea.
Drug Interactions: This medication can interact with several other drugs (e.g., amiodarone for heart rhythms, or rifampin). Always provide your healthcare provider with a full list of your current medications.
City Drug House Exporters provides:
Bulk supply for hospitals & distributors
Export to USA. Washington, INDIA
Regulatory documents (COA, MSDS, etc.)
Competitive pricing & reliable logistics
Contact for More Information :
📞 Contact City drug House Exporters from India
🌐 Websites:
https://www.citydrugexporters.com
📧 Email: citydrug123@gmail.com
📦 Business Type: Exporter | Bulk Supplier | Distributor
📲 WhatsApp: +91 9975390171
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