Leading Ketoplast +Plaster (Ketoprofen) Supplier from INDIA to Washington, USA | City Drug Exporters
City Drug Exporters supplies Ketoplast + Plaster (Ketoprofen) from INDIA to Washington, USA. Trusted pharmaceutical exporter for wholesalers, distributors, pharmacies, and healthcare procurement companies.
Ketoplast Plus is a medicated transdermal plaster containing Ketoprofen (usually 30 mg), a potent Non-Steroidal Anti-Inflammatory Drug (NSAID). It is widely used in Nagpur for localized, symptomatic relief of muscle and joint pain, soft tissue injuries, sprains, and backache.
Pharmacodynamics
Mechanism of Action: Ketoprofen reduces pain and swelling by inhibiting the (COX) enzyme system (Cyclooxygenase-1 and Cyclooxygenase-2), which prevents the body from synthesizing prostaglandins—the primary chemical messengers that trigger pain and inflammation.
Targeted Action: The plaster releases the drug steadily into the local tissues. Unlike oral painkillers that travel through the entire gastrointestinal tract, the transdermal delivery provides high localized drug concentrations at the site of injury while significantly reducing the risk of systemic side effects.
Analgesic Effect: In addition to its anti-inflammatory properties, ketoprofen provides analgesic effects by inhibiting spinal cord nociceptor reflex activity, limiting central sensitization.
Pharmacokinetics (Movement in the body)Absorption: The active ingredient permeates the stratum corneum (the top layer of skin) to enter the local subcutaneous tissues, muscles, and joint spaces.
Onset & Duration: It typically begins providing relief within 30 minutes, with sustained-release pharmacokinetics allowing for 12 to 24 hours of continued pain management.
Metabolism & Excretion: Because it acts locally, systemic concentrations remain very low. The small amount that enters the bloodstream is primarily metabolized in the liver and excreted by the kidneys.
City Drug House Exporters provides:
Bulk supply for hospitals & distributors
Export to USA. Washington, INDIA
Regulatory documents (COA, MSDS, etc.)
Competitive pricing & reliable logistics
Contact for More Information :
📞 Contact City drug House Exporters from India
🌐 Websites:
https://www.citydrugexporters.com
📧 Email: citydrug123@gmail.com
📦 Business Type: Exporter | Bulk Supplier | Distributor
📲 WhatsApp: +91 9975390171
