Leading KETOCIP Supplier from INDIA to Washington, USA | City Drug Exporters
City Drug Exporters supplies KETOCIP from INDIA to Washington, USA. Trusted pharmaceutical exporter for wholesalers, distributors, pharmacies, and healthcare procurement companies
KETOCIP is a brand name for medications containing the active antifungal ingredient ketoconazole. It treats fungal infections by disrupting the fungal cell membrane, resulting in fungal cell death.
Mechanism of Action (Pharmacodynamics)
Ketoconazole is a broad-spectrum imidazole antifungal agent.
Ergosterol Inhibition: It primarily works by inhibiting the enzyme fungal cytochrome P-450 14α-demethylase.
Cell Membrane Destruction: This enzyme converts lanosterol to ergosterol, a vital component of fungal cell membranes. By blocking this synthesis, the fungal cell membrane becomes highly permeable and dysfunctional, which inhibits fungal growth and eventually causes cell death.
Pharmacokinetics
Absorption: Oral tablets require an acidic stomach environment to dissolve and absorb effectively into the bloodstream. Topical applications (like KetoCIP Shampoo) have negligible systemic absorption and act locally on the skin or scalp.
Distribution: Systemic oral doses distribute widely throughout the body but do not enter the cerebrospinal fluid or brain effectively.
Metabolism: It is extensively metabolized in the liver, primarily via the hepatic cytochrome P450 (CYP3A4) system.
Elimination: The drug and its metabolites are excreted primarily in the bile and feces, with only a small portion excreted via the urine.
City Drug House Exporters provides:
Bulk supply for hospitals & distributors
Export to USA. Washington, INDIA
Regulatory documents (COA, MSDS, etc.)
Competitive pricing & reliable logistics
Contact for More Information :
📞 Contact City drug House Exporters from India
🌐 Websites:
https://www.citydrugexporters.com
📧 Email: citydrug123@gmail.com
📦 Business Type: Exporter | Bulk Supplier | Distributor
📲 WhatsApp: +91 9975390171
