Hertraz 440mg Injection (Trastuzumab)
Therapeutic Classification
1.Antineoplastic Agents: Medicines used to treat cancer.
2.Monoclonal Antibodies (mAb): A type of protein designed to recognize and bind to specific targets in the body.
3.Targeted Biological Therapy: Focuses specifically on cancer cells with high levels of the HER2 protein, aiming to minimize damage to healthy cells.
4.HER2 Inhibitor: Specifically inhibits the Human Epidermal Growth Factor Receptor 2.
Mechanism of Action (Pharmacodynamics)
1.Recombinant Humanized IgG1 Antibody: Expressed in Chinese hamster ovary (CHO) cells.
2.HER2 Receptor Inhibition: Binds to the extracellular domain of the HER2 protein, preventing the signaling pathways that cause rapid, uncontrolled proliferation of cancer cells.
3.Antibody-Dependent Cellular Cytotoxicity (ADCC): Mediates the destruction of HER2-positive cancer cells by the body’s immune system.
Clinical Pharmacology and Applications
1.HER2-Positive Breast Cancer: Indicated for early and metastatic breast cancer that overexpresses the HER2 protein.
2.HER2-Positive Gastric Cancer: Indicated for advanced stomach or gastroesophageal junction adenocarcinoma.
Pharmacokinetic and Safety Tags
1.Intravenous Infusion: Administered solely via IV by a medical professional.
2.Cardiotoxicity: Known to cause potential heart-related side effects, necessitating cardiac monitoring.
3.Adverse Reactions: Common effects include infusion-related reactions, fever, nausea, vomiting, diarrhea, and neutropenia.
4.Storage Requirement: Must be stored in a refrigerator (2°C - 8°C) and protected from light.
City Drug House Exporters provides:
Bulk supply for hospitals & distributors
Export to USA. Washington, INDIA
Regulatory documents (COA, MSDS, etc.)
Competitive pricing & reliable logistics
Contact for More Information :
📞 Contact City drug House Exporters from India
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📦 Business Type: Exporter | Bulk Supplier | Distributor
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