Leading Frasix 40 Injection (Furosemide) Supplier from INDIA to Washington, USA | City Drug Exporters
City Drug Exporters supplies Frasix 40 Injection (Furosemide) from INDIA to Washington, USA. Trusted pharmaceutical exporter for wholesalers, distributors, pharmacies, and healthcare procurement companies
Frasix 40 Injection (Furosemide) is a potent loop diuretic used to rapidly remove excess fluid (edema) and manage high blood pressure. It is primarily administered in clinical or hospital settings for critical conditions like acute pulmonary edema, congestive heart failure, and severe fluid retention linked to kidney or liver diseases.
Mechanism of Action
Primary Site of Action: Acts on the thick ascending limb of the loop of Henle in the kidneys.
Receptor Inhibition: Competitively blocks the Sodium-Potassium-Chloride (NaβΊ-KβΊ-2Clβ») cotransporter.
Result: Prevents the reabsorption of sodium and chloride back into the bloodstream.
Physiological Effects
Diuresis: Traps sodium, chloride, and water in the renal tubule, significantly increasing urine output.
Electrolyte Excretion: Increases the excretion of potassium, magnesium, calcium, and hydrogen ions.
Vasodilation: Produces a rapid venodilatory effect that reduces left ventricular end-diastolic pressure, providing fast relief during acute pulmonary edema even before diuresis fully begins
Pharmacokinetics :
Onset of Action: Intravenous (IV) injection works within 5 minutes, peaking around 30 minutes.
Duration of Action: The diuretic effect lasts for about 2 hours.
Metabolism: Partially metabolized in the liver; primarily excreted by the kidneys
City Drug House Exporters provides:
Bulk supply for hospitals & distributors
Export to USA. Washington, INDIA
Regulatory documents (COA, MSDS, etc.)
Competitive pricing & reliable logistics
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