Leading Estrabet Gel 80 g (0.06 % w/w estradiol) Supplier from INDIA to Washington, USA | City Drug Exporters
City Drug Exporters supplies Estrabet Gel 80 g (0.06 % w/w estradiol) from INDIA to Washington, USA. Trusted pharmaceutical exporter for wholesalers, distributors, pharmacies, and healthcare procurement companies
Estrabet Gel 80 g (0.06 % w/w estradiol) is a topical hormone replacement therapy (HRT) used to treat estrogen deficiencies. It works by supplementing declining estradiol levels to manage menopausal symptoms (hot flashes, vaginal dryness) and prevent bone loss (osteoporosis) in postmenopausal women.
Mechanism of Action: As an estrogen, it binds to nuclear receptors in estrogen-responsive tissues (e.g., female reproductive tract, breast, pituitary, hypothalamus, and liver). This modulates the transcription of target genes, thereby restoring physiological estrogen levels and reversing menopausal symptoms and vaginal atrophy.
Pharmacokinetics (Topical):
Absorption: Applied directly to the skin, it bypasses the 'first-pass' metabolism of the liver—which occurs with oral estrogens—allowing for consistent, sustained systemic circulation.
Metabolism: It is primarily metabolized in the liver to estrone and estriol, and then conjugated to glucuronides and sulfates.
Excretion: Metabolites are excreted primarily via the kidneys in the urine.
Clinical Indications:
Management of moderate-to-severe vasomotor symptoms (hot flushes) associated with menopause.
Treatment of vulvar and vaginal atrophy.
Prevention of postmenopausal osteoporosis.
City Drug House Exporters provides:
Bulk supply for hospitals & distributors
Export to USA. Washington, INDIA
Regulatory documents (COA, MSDS, etc.)
Competitive pricing & reliable logistics
Contact for More Information :
📞 Contact City drug House Exporters from India
🌐 Websites:
https://www.citydrugexporters.com
📧 Email: citydrug123@gmail.com
📦 Business Type: Exporter | Bulk Supplier | Distributor
📲 WhatsApp: +91 9975390171
