Leading ESOMECAN 40 Injection (Eomeprazole) Supplier from INDIA to Washington, USA | City Drug Exporters
City Drug Exporters supplies ESOMECAN 40 Injection (Eomeprazole) from INDIA to Washington, USA. Trusted pharmaceutical exporter for wholesalers, distributors, pharmacies, and healthcare procurement companies
ESOMECAN 40 Injection (manufactured by American Remedies) contains esomeprazole, which is a Proton Pump Inhibitor (PPI) medication. It is used clinically to treat conditions involving excessive stomach acid, such as gastroesophageal reflux disease (GERD), erosive esophagitis, peptic ulcers, and Zollinger-Ellison syndrome. The injection form provides rapid gastric acid suppression when oral administration is not possible.
Mechanism of Action :
Proton Pump Inhibition: It binds to and inhibits the H⁺/K⁺-ATPase enzyme system (the 'proton pump').
Acid Suppression: This action stops the final step of acid secretion in the gastric parietal cells.
pH Increase: It raises stomach pH, promoting the healing of esophageal or gastric mucosal damage.
Pharmacokinetics
Onset: Rapid inhibition of acid secretion occurs shortly after intravenous administration.
Metabolism: Extensively metabolized in the liver by the cytochrome P450 (CYP2C19 and CYP3A4) enzyme system.
Half-Life: Approximately 1 to 1.5 hours, but the duration of acid suppression lasts much longer due to the irreversible binding to proton pumps.
Excretion: Metabolites are primarily excreted through the kidneys.
Dosage and Administration :
Administration: It is a powder in a vial that is reconstituted and given slowly as an intravenous injection or infusion.
Supervision: Must be administered by a healthcare professional in a clinical setting.
Dosing: Typically 40 mg once or twice daily, depending on the severity of the condition being treated.
Common Side Effects :
Gastrointestinal: Diarrhea, nausea, vomiting, constipation, or abdominal pain.
General: Headache and dizziness.
Long-term Risks: Prolonged use may rarely be associated with decreased vitamin B₁₂ absorption or bone fractures
City Drug House Exporters provides:
Bulk supply for hospitals & distributors
Export to USA. Washington, INDIA
Regulatory documents (COA, MSDS, etc.)
Competitive pricing & reliable logistics
Contact for More Information :
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