Leading Eptocan Injection Supplier from INDIA to Washington, USA | City Drug Exporters
City Drug Exporters supplies Eptocan Injection, from INDIA to Washington, USA. Trusted pharmaceutical exporter for wholesalers, distributors, pharmacies, and healthcare procurement companies
Eptocan Injection is primarily formulated with Etoposide, a cytotoxic chemotherapy agent used to treat cancers such as testicular cancer, small-cell lung cancer (SCLC), lymphomas, and leukemias .
Etoposide: Mechanism of Action
Topoisomerase II Inhibition: Etoposide binds to and inhibits the enzyme topoisomerase II, preventing DNA re-ligation.
DNA Strand Breaks: It stabilizes a 'cleavage complex', resulting in permanent single- and double-strand DNA breaks.
Apoptosis: The accumulation of unrepairable DNA fragments leads to cell death (apoptosis).
Cell Cycle Phase: It primarily targets the premitotic stages, acting specifically in the S phase and G2 phase of cell division.
Pharmacokinetics :
Administration: Administered strictly via slow intravenous (IV) infusion to avoid severe infusion-related hypotension.
Metabolism: Primarily metabolized in the liver.
Excretion: Excreted mainly through the urine (30% to 70%), with a smaller fraction excreted in the feces.
Half-life: The terminal elimination half-life ranges from 4 to 6 hours.
Adverse Effects :
Myelosuppression: Dose-limiting bone marrow suppression resulting in neutropenia, anemia, and thrombocytopenia.
Gastrointestinal: Nausea, vomiting, diarrhea, and loss of appetite.
Alopecia: Temporary hair loss.
Hypotension: Rapid infusion can cause a drop in blood pressure.
Contraindications & Precautions :
Hypersensitivity: Contraindicated in patients with a history of allergic reactions to Etoposide.
Hepatic/Renal Impairment: Dose adjustments may be required for patients with compromised liver or kidney function.
Blood Monitoring: Complete blood counts (CBC) and organ function tests are required before and during every treatment cycle
City Drug House Exporters provides:
Bulk supply for hospitals & distributors
Export to USA. Washington, INDIA
Regulatory documents (COA, MSDS, etc.)
Competitive pricing & reliable logistics
Contact for More Information :
📞 Contact City drug House Exporters from India
🌐 Websites:
https://www.citydrugexporters.com
📧 Email: citydrug123@gmail.com
📦 Business Type: Exporter | Bulk Supplier | Distributor
📲 WhatsApp: +91 9975390171
