Leading Enfiera 500 Supplier from INDIA to Washington, USA | City Drug Exporters
City Drug Exporters supplies Enfiera 500 from INDIA to Washington, USA. Trusted pharmaceutical exporter for wholesalers, distributors, pharmacies, and healthcare procurement companies
Enfiera 500 is an injectable prescription medication primarily used to treat certain blood cancers and severe autoimmune conditions. Its active ingredient is Rituximab, a targeted monoclonal antibody that eliminates harmful B-lymphocyte white blood cells.
Mechanism of Action (MOA)
Rituximab specifically targets and binds to the CD20 antigen, a protein found on the surface of pre-B and mature B-lymphocytes. Once bound to a B-cell, the drug triggers the destruction of that cell through several pathways :
Complement-Dependent Cytotoxicity (CDC): Activates the immune system's complement cascade to destroy the B-cell.
Antibody-Dependent Cellular Cytotoxicity (ADCC): Recruits natural killer cells and macrophages to attack and kill the B-cell.
Direct Apoptosis: Induces direct programmed cell death in the B-cell.
Cytokine Inhibition: Blocks the production of proinflammatory cytokines and suppresses rheumatoid factor production to alleviate inflammation in autoimmune diseases.
Pharmacokinetics ;
Administration: Administered via intravenous (IV) infusion following appropriate dilution.
Metabolism: Cleared by the reticuloendothelial system; metabolized by proteolytic enzymes.
Half-Life: Highly variable depending on the patient's condition and repeated dosing, but generally ranges from 18 to 22 days.
Duration of Effect: B-cell depletion typically lasts for 6 to 9 months after completing a full course of treatment.
City Drug House Exporters provides:
Bulk supply for hospitals & distributors
Export to USA. Washington, INDIA
Regulatory documents (COA, MSDS, etc.)
Competitive pricing & reliable logistics
Contact for More Information :
📞 Contact City drug House Exporters from India
🌐 Websites:
https://www.citydrugexporters.com
📧 Email: citydrug123@gmail.com
📦 Business Type: Exporter | Bulk Supplier | Distributor
📲 WhatsApp: +91 9975390171
