Leading Drotacan Injection (Drotaverine Hydrochloride)Supplier from INDIA to Washington, USA | City Drug Exporters
City Drug Exporters supplies Drotacan Injection (Drotaverine Hydrochloride), from INDIA to Washington, USA. Trusted pharmaceutical exporter for wholesalers, distributors, pharmacies, and healthcare procurement companies
Drotacan Injection (Drotaverine Hydrochloride) is a potent, non-anticholinergic antispasmodic medication used to rapidly relieve painful smooth muscle spasms. It is primarily administered intravenously or intramuscularly to treat conditions like renal colic, biliary colic, and gastrointestinal spasms.
Mechanism of Action :
Drotaverine operates primarily at the cellular level by targeting the biochemical pathways responsible for muscle contraction.
PDE-IV Inhibition: It inhibits the Phosphodiesterase-4 (PDE-4) enzyme.
cAMP Accumulation: This enzyme breakdown blockage raises intracellular levels of cyclic AMP (cAMP).
Calcium Regulation: Elevated cAMP decreases cellular calcium uptake, preventing muscle fibers from contracting.
Direct Relaxation: This directly relaxes smooth muscles in the gastrointestinal, biliary, urinary, and reproductive tracts.
Pharmacokinetics ;
Onset of Action: Works very rapidly (within 2 to 5 minutes) when given intravenously.
Metabolism: Metabolized heavily in the liver.
Excretion: Primarily excreted via the kidneys (urine) and the biliary tract (feces).
Side Effects and Precautions :
Common Side Effects: Includes nausea, dizziness, dry mouth, and injection-site flushing.
Cardiovascular Effect: It can cause a temporary drop in blood pressure (hypotension).
Caution: Should be used cautiously in patients with severe heart, liver, or kidney disease.
Independence: It is not habit-forming and causes no sedation.
City Drug House Exporters provides:
Bulk supply for hospitals & distributors
Export to USA. Washington, INDIA
Regulatory documents (COA, MSDS, etc.)
Competitive pricing & reliable logistics
Contact for More Information :
📞 Contact City drug House Exporters from India
🌐 Websites:
https://www.citydrugexporters.com
📧 Email: citydrug123@gmail.com
📦 Business Type: Exporter | Bulk Supplier | Distributor
📲 WhatsApp: +91 9975390171
City Drug Exporters supplies Drotacan Injection (Drotaverine Hydrochloride), from INDIA to Washington, USA. Trusted pharmaceutical exporter for wholesalers, distributors, pharmacies, and healthcare procurement companies
Drotacan Injection (Drotaverine Hydrochloride) is a potent, non-anticholinergic antispasmodic medication used to rapidly relieve painful smooth muscle spasms. It is primarily administered intravenously or intramuscularly to treat conditions like renal colic, biliary colic, and gastrointestinal spasms.
Mechanism of Action :
Drotaverine operates primarily at the cellular level by targeting the biochemical pathways responsible for muscle contraction.
PDE-IV Inhibition: It inhibits the Phosphodiesterase-4 (PDE-4) enzyme.
cAMP Accumulation: This enzyme breakdown blockage raises intracellular levels of cyclic AMP (cAMP).
Calcium Regulation: Elevated cAMP decreases cellular calcium uptake, preventing muscle fibers from contracting.
Direct Relaxation: This directly relaxes smooth muscles in the gastrointestinal, biliary, urinary, and reproductive tracts.
Pharmacokinetics ;
Onset of Action: Works very rapidly (within 2 to 5 minutes) when given intravenously.
Metabolism: Metabolized heavily in the liver.
Excretion: Primarily excreted via the kidneys (urine) and the biliary tract (feces).
Side Effects and Precautions :
Common Side Effects: Includes nausea, dizziness, dry mouth, and injection-site flushing.
Cardiovascular Effect: It can cause a temporary drop in blood pressure (hypotension).
Caution: Should be used cautiously in patients with severe heart, liver, or kidney disease.
Independence: It is not habit-forming and causes no sedation.
City Drug House Exporters provides:
Bulk supply for hospitals & distributors
Export to USA. Washington, INDIA
Regulatory documents (COA, MSDS, etc.)
Competitive pricing & reliable logistics
Contact for More Information :
📞 Contact City drug House Exporters from India
🌐 Websites:
https://www.citydrugexporters.com
📧 Email: citydrug123@gmail.com
📦 Business Type: Exporter | Bulk Supplier | Distributor
📲 WhatsApp: +91 9975390171
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