Leading Dr. D3 (Vitamin D3 ) Supplier from INDIA to Washington, USA | City Drug Exporters
City Drug Exporters supplies Dr. D3 (Vitamin D3) from INDIA to Washington, USA. Trusted pharmaceutical exporter for wholesalers, distributors, pharmacies, and healthcare procurement companies
The pharmacological combination of Vitamin D3 (cholecalciferol) and Vitamin K2 (menaquinone) creates a vital biochemical synergy that regulates calcium metabolism. Vitamin D3 increases intestinal calcium absorption, while Vitamin K2 directs that calcium into the bones and teeth, preventing it from accumulating in blood vessels and soft tissues.
Mechanism of Action
Vitamin D3: Acts as a prohormone. It promotes the synthesis of Vitamin K-dependent proteins in the body.
Vitamin K2: Activates these specialized proteins, specifically osteocalcin and matrix Gla-protein (MGP).
Osteocalcin: Binds free calcium to the bone matrix to increase bone mineral density.
Matrix Gla-protein: Clears calcium from arterial walls, supporting cardiovascular flexibility and reducing vascular calcification risks.
Pharmacokinetics :
Absorption: Both are fat-soluble micronutrients. They require dietary fats and bile acids for optimal absorption in the small intestine.
Transport: Absorbed nutrients are incorporated into chylomicrons and transported via the lymphatic system into the bloodstream.
Metabolism (D3): Converted in the liver to 25-hydroxyvitamin D, then converted by the kidneys into 1, 25-dihydroxyvitamin D (the active form).
Metabolism (K2): Specifically the MK-7 form has a longer half-life (about 3 days) compared to other Vitamin K forms, providing continuous systemic circulation.
City Drug House Exporters provides:
Bulk supply for hospitals & distributors
Export to USA. Washington, INDIA
Regulatory documents (COA, MSDS, etc.)
Competitive pricing & reliable logistics
Contact for More Information :
📞 Contact City drug House Exporters from India
🌐 Websites:
https://www.citydrugexporters.com
📧 Email: citydrug123@gmail.com
📦 Business Type: Exporter | Bulk Supplier | Distributor
📲 WhatsApp: +91 9975390171
