Leading Dr. D3 (Vitamin D3 / Cholecalciferol) Supplier from INDIA to Washington, USA | City Drug Exporters
City Drug Exporters supplies Dr. D3 (Vitamin D3 / Cholecalciferol) from INDIA to Washington, USA. Trusted pharmaceutical exporter for wholesalers, distributors, pharmacies, and healthcare procurement companies
Dr. D3 (Vitamin D3) contains cholecalciferol, a naturally occurring, fat-soluble form of vitamin D. Its primary pharmacological action is to stimulate the intestinal absorption of calcium and phosphorus. This maintains adequate serum calcium and phosphate levels, which are critical for normal bone mineralization, muscle contraction, nerve conduction, and immune system function.
Mechanism of Action :
Endogenous Synthesis: UV light converts 7-dehydrocholesterol to previtamin D3 in the skin.
First Hydroxylation: The liver converts both absorbed supplements and skin-synthesized vitamin D3 into calcifediol (25-hydroxycholecalciferol).
Second Hydroxylation: The kidneys convert calcifediol into the highly active metabolite calcitriol (1, 25-dihydroxycholecalciferol).
Receptor Binding: Calcitriol binds to intracellular Vitamin D Receptors (VDRs) in the intestines, bones, and kidneys.
Calcium Mobilization: This VDR activation promotes active transport of calcium and phosphorus across the intestinal mucosa into the bloodstream.
Pharmacokinetics :
Absorption: It is absorbed passively in the small intestine, requiring bile salts and pancreatic enzymes for fat emulsion and breakdown.
Distribution: It is transported in the blood bound to Vitamin D-Binding Protein (DBP) and stored primarily in adipose (fat) tissue and muscle.
Metabolism: Primarily metabolized in the liver and kidneys to reach its active form.
Excretion: Primarily excreted via the bile and feces, with only a small fraction eliminated in the urine.
City Drug House Exporters provides:
Bulk supply for hospitals & distributors
Export to USA. Washington, INDIA
Regulatory documents (COA, MSDS, etc.)
Competitive pricing & reliable logistics
Contact for More Information :
📞 Contact City drug House Exporters from India
🌐 Websites:
https://www.citydrugexporters.com
📧 Email: citydrug123@gmail.com
📦 Business Type: Exporter | Bulk Supplier | Distributor
📲 WhatsApp: +91 9975390171
