Exporter India Doxorubin 50 mg/25 ml Injection (Doxorubicin Hydrochloride) Bulk Supply Oncology Drugs .
Buy Doxorubin 50 mg/25 ml Injection (Doxorubicin Hydrochloride) in bulk from India. Leading oncology drug exporter City Drug House Exporters offering global supply with latest regulatory updates and competitive pricing.
Drug Class: Anthracycline, Antibiotic, Cytotoxic Anti-neoplastic Agent.
Mechanism of Action (MOA): Topoisomerase II Inhibitor, DNA Intercalation, Free Radical Generation.
Administration: Intravenous (IV) injection only.
Common Indications: Breast cancer, Acute lymphoblastic leukemia (ALL), Acute myeloid leukemia (AML), Hodgkin/non-Hodgkin lymphoma, Bladder cancer, Ovarian cancer.
Key Toxicities: Cardiotoxicity (cardiomyopathy/arrhythmias), Myelosuppression (bone marrow suppression), Extravasation (tissue necrosis), Alopecia, Stomatitis.
Doxorubicin induces DNA damage through three main mechanisms:
Intercalation: Inserts into the DNA double helix, inhibiting DNA and RNA synthesis.
Topoisomerase II Inhibition: Prevents DNA repair by inhibiting topoisomerase II.
Free Radicals: Generates harmful free radicals that damage cell membranes, DNA, and proteins.
Pharmacokinetics
Distribution: High, with a rapid initial distribution half-life.
Metabolism: Extensively metabolized in the liver to the active metabolite, doxorubicinol.
Elimination: Primarily through biliary excretion, with a terminal half-life of 20 to 48 hours.
City Drug House Exporters provides:
Bulk supply for hospitals & distributors
Export to USA. Washington, INDIA
Regulatory documents (COA, MSDS, etc.)
Competitive pricing & reliable logistics
Contact for More Information :
📞 Contact City drug House Exporters from India
🌐 Websites: https://www.citydrugexporters.com
📧 Email: citydrug123@gmail.com
📦 Business Type: Exporter | Bulk Supplier | Distributor
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