Leading Dopacan 200 mg Injection Supplier from INDIA to Washington, USA | City Drug Exporters
City Drug Exporters supplies Dopacan 200 mg Injection from INDIA to Washington, USA. Trusted pharmaceutical exporter for wholesalers, distributors, pharmacies, and healthcare procurement companies
Dopacan 200 mg Injection is an intravenous medication containing dopamine. It is a potent inotropic and vasopressor agent used in intensive care to treat severe low blood pressure, heart failure, and shock. Its pharmacological effects are strictly dose-dependent, acting on different receptors as the infusion rate changes.
Mechanism of Action :
Dopamine stimulates distinct receptors based on the dosage administered:
Low dose (1 - 5 μ g/kg/min): Stimulates dopaminergic receptors, dilating renal, mesenteric, and coronary arteries, thereby increasing urine output and blood flow to the kidneys.
Intermediate dose (5 - 15 μ g/kg/min): Stimulates β₁-adrenergic receptors in the heart, boosting myocardial contractility, heart rate, and overall cardiac output.
High dose (>15 μ g/kg/min): Stimulates α₁-adrenergic receptors, causing peripheral vasoconstriction and significantly increasing systemic blood pressure.
Administration and Pharmacokinetics
Delivery: Administered strictly via continuous intravenous (IV) infusion under medical supervision.
Onset and Duration: Action begins within 2 to 5 minutes of starting the infusion and lasts less than 10 minutes after the infusion stops.
Metabolism: Rapidly metabolized in the liver, kidneys, and plasma by monoamine oxidase (MAO) and catechol-O-methyltransferase (COMT).
Half-Life: Approximately 2 minutes.
Side Effects and Contraindications
Common Side Effects: Palpitations, irregular heartbeat (tachyarrhythmias), nausea, vomiting, headache, and chest pain.
Absolute Contraindications: Patients with a pheochromocytoma (a rare adrenal gland tumor), uncorrected tachyarrhythmias, or ventricular fibrillation.
Warning: Care must be taken to correct hypovolemia (low blood volume) with fluid replacement before initiating dopamine therapy
City Drug House Exporters provides:
Bulk supply for hospitals & distributors
Export to USA. Washington, INDIA
Regulatory documents (COA, MSDS, etc.)
Competitive pricing & reliable logistics
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