City Drug House Exporters | Hepatitis Medicines Supplier to Washington, USA, INDIA
City Drug House Exporters supplies and exports high-quality hepatitis medicines from India to Washington, USA with trusted pharma solutions and timely global delivery.
Daclacure (Daclatasvir) 60mg is a direct-acting antiviral (DAA) medication used to treat chronic Hepatitis C Virus (HCV) infection. It works by inhibiting the NS5A protein, effectively preventing the virus from multiplying and spreading in the body.
Mechanism of Action
Target: It specifically targets the HCV NS5A protein, a non-structural phosphoprotein that is critical for viral replication, assembly, and the formation of replication complexes.
Action: By binding to the N-terminus of the NS5A domain, it blocks interactions with host cell proteins, disrupting the virus's ability to multiply.
Result: It causes a rapid, significant reduction in viral load, and over a sustained treatment period (typically 12 to 24 weeks), helps clear the virus from the bloodstream.
Pharmacokinetics :
Bioavailability: The oral bioavailability of the tablet is approximately 67%.
Metabolism: It is primarily metabolized in the liver by the cytochrome P450 3A4 (CYP3A4) enzyme system.
Excretion: Excretion occurs primarily through the feces (53%) and to a lesser extent via the urine (8.8%).
Administration & Drug Interactions
Combination Therapy: Daclatasvir is never used as a standalone treatment. It is co-administered with other antivirals like Sofosbuvir and/or Ribavirin.
Contraindications & Interactions: Because it is a substrate of CYP3A4, medications that induce or inhibit this enzyme can alter Daclatasvir levels. It should not be used with strong CYP3A4 inducers like rifampin, phenytoin, carbamazepine, or St. John's wort.
City Drug House Exporters provides:
Bulk supply for hospitals & distributors
Export to USA. Washington, INDIA
Regulatory documents (COA, MSDS, etc.)
Competitive pricing & reliable logistics
Contact for More Information :
📞 Contact City drug House Exporters from India
🌐 Websites:
https://www.citydrugexporters.com
📧 Email: citydrug123@gmail.com
📦 Business Type: Exporter | Bulk Supplier | Distributor
📲 WhatsApp: +91 9975390171
