Cytocarb 450mg Injection (Carboplatin) Exporter | India Supplier – City Drug Exporters Cytocarb 450mg Injection (Carboplatin).
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CYTOCARB 450MG is an anticancer medicine. It acts by damaging the genetic material (DNA and RNA) of the cancer cells. This prevents the cancer cells from growing and multiplying within the body.
Pharmacological Action
1.Mechanism of Action: Carboplatin acts as an alkylating agent. It enters cells, where the platinum complex interacts with DNA to form intra-strand and inter-strand cross-links. This damage interferes with DNA repair and synthesis, arresting cell division and leading to apoptosis (programmed cell death).
2.Target: Primarily affects rapidly dividing cells, particularly in cancers of the ovary and lungs.
Pharmacokinetics
1.Administration: Intravenous (IV) infusion.
2.Onset of Action: Peak plasma levels are observed within 2 to 4 hours post-administration.
3.Duration of Effect: The effect typically lasts for an average of 24 hours.
4.Metabolism & Excretion: It is heavily excreted through the kidneys. Patients with renal impairment (creatinine clearance
mL/min) are at higher risk of toxicity.
Clinical Uses
1.Ovarian Cancer: Advanced epithelial ovarian cancer.
2.Small Cell Lung Cancer (SCLC): As a single agent or in combination with other chemotherapy agents.
3.Other Potential Uses: Breast, head and neck, bladder, and brain cancers.
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