Cytoblastin 10mg Injection (Vinblastine) Exporter | India Supplier – City Drug Exporters Cytoblastin 10mg Injection (Vinblastine) from India.
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Pharmacology of Cytoblastin (Vinblastine) 10mg Injection:
1. Mechanism of Action: It binds to tubulin, a protein necessary for cell division, thereby inhibiting microtubule formation and causing the mitotic spindle to break down. This arrests cells in the M-phase and disrupts DNA replication in the S-phase, stopping the proliferation of cancer cells.
2.Administration: It must be administered strictly as an intravenous (IV) infusion or injection by a qualified healthcare professional, usually in a clinical setting. Note: It can be fatal if given by other routes.
3.Uses: It is used in treating various cancers, including Hodgkin's disease, lymphomas, testicular cancer, and advanced breast cancer.
4.Common Side Effects: Frequently reported side effects include bone marrow suppression (decreased white blood cell count), nausea, vomiting, loss of appetite, constipation, abdominal pain, and temporary hair loss.
5.Serious Warnings: It is unsafe during pregnancy (potential fetal risk) and breastfeeding. It may cause severe nerve damage, and long-term effects can include infertility or damage to the heart and kidneys.
6.Monitoring: Regular monitoring of blood counts (platelets, white blood cells) and liver function is necessary during treatment.
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