Leading CPM Injection, (Chlorpheniramine Maleate) Supplier from INDIA to Washington, USA | City Drug Exporters
City Drug Exporters supplies CPM Injection, (Chlorpheniramine Maleate), from INDIA to Washington, USA. Trusted pharmaceutical exporter for wholesalers, distributors, pharmacies, and healthcare procurement companies
CPM Injection, (Chlorpheniramine Maleate), is a potent, first-generation H₁ antihistamine. It is widely used for the rapid management of acute allergic reactions, anaphylaxis, and blood transfusion reactions.
Mechanism of Action :
Receptor Antagonism: Competitively and reversibly binds to H₁ histamine receptors.
Histamine Blockade: Prevents the physiological effects of histamine, such as vasodilation, increased vascular permeability, and bronchoconstriction.
Cellular Inhibition: Reduces inflammatory cytokines (like NF-κ B) and enhances eosinophilic apoptosis.
Pharmacokinetics :
Absorption: Bioavailability is highly systemic; reaches rapid peak plasma concentrations via IM or IV routes.
Distribution: Highly bound to plasma proteins (roughly 70%).
Metabolism: Extensively metabolized in the liver, primarily via the cytochrome P450 system (CYP2D6) into active/inactive metabolites.
Excretion: Excreted primarily by the kidneys in the form of metabolites.
Dosage and Administration :
Adult Dose: Typically 10 mg to 20 mg administered via slow IV, IM, or subcutaneous routes.
Maximum Limit: Must not exceed 40 mg in a 24-hour period.
Administration Note: IV administration should be done slowly to prevent a sudden drop in blood pressure.
Side Effects & Contraindications :
CNS Effects: High tendency to cause drowsiness, sedation, and lethargy due to blood-brain barrier penetration.
Anticholinergic effects: Blurred vision, dry mouth, and urinary retention.
Precautions: Avoid in patients with glaucoma, prostatic hyperplasia, or severe asthma.
City Drug House Exporters provides:
Bulk supply for hospitals & distributors
Export to USA. Washington, INDIA
Regulatory documents (COA, MSDS, etc.)
Competitive pricing & reliable logistics
Contact for More Information :
📞 Contact City drug House Exporters from India
🌐 Websites:
https://www.citydrugexporters.com
📧 Email: citydrug123@gmail.com
📦 Business Type: Exporter | Bulk Supplier | Distributor
📲 WhatsApp: +91 9975390171
