Leading Canrise D3 6L Injection Supplier from INDIA to Washington, USA | City Drug Exporters
City Drug Exporters supplies Canrise D3 6L Injection from INDIA to Washington, USA. Trusted pharmaceutical exporter for wholesalers, distributors, pharmacies, and healthcare procurement companies
Canrise D3 6L Injection contains 600, 000 I.U. of Cholecalciferol (Vitamin D₃). It is used to rapidly correct severe Vitamin D deficiency and manage related bone conditions like osteoporosis and osteomalacia by optimizing calcium and phosphate absorption.
Mechanism of Action: Cholecalciferol is converted in the liver to calcifediol, and then in the kidneys to calcitriol (the active form of Vitamin D). Calcitriol binds to intracellular Vitamin D Receptors (VDR) in the small intestine, kidneys, and bones. This action stimulates the synthesis of calcium-binding proteins, directly promoting the active absorption of calcium and phosphate from the gut.
Bone Remodeling: By maintaining adequate serum calcium and phosphate levels, calcitriol ensures proper mineralization of bone matrix and prevents excessive parathyroid hormone (PTH) secretion, which limits bone resorption.
Pharmacokinetics:
Administration: Typically administered via deep intramuscular (IM) injection (often in the gluteal muscle). It should only be given by a healthcare professional.
Onset of Action: As it is a high-dose depot injection, it provides a sustained release of the vitamin over several weeks.
Distribution: Stored primarily in fat tissue and the liver.
Metabolism & Excretion: Metabolized in the liver and kidneys, with primary excretion occurring via the bile into the feces, and a small amount in the urine.
City Drug House Exporters provides:
Bulk supply for hospitals & distributors
Export to USA. Washington, INDIA
Regulatory documents (COA, MSDS, etc.)
Competitive pricing & reliable logistics
Contact for More Information :
📞 Contact City drug House Exporters from India
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📦 Business Type: Exporter | Bulk Supplier | Distributor
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