Leading Cortican 100 Injection (hydrocortisone sodium succinate)Supplier from INDIA to Washington, USA | City Drug Exporters
City Drug Exporters supplies Atranium 50 mg Injection (Atracurium Besylate) from INDIA to Washington, USA. Trusted pharmaceutical exporter for wholesalers, distributors, pharmacies, and healthcare procurement companies
Atranium 50 mg Injection (Atracurium Besylate) is a non-depolarizing skeletal muscle relaxant. It is administered intravenously by anesthetists during general anesthesia to facilitate endotracheal intubation, support controlled mechanical ventilation, and enable surgeons to perform procedures without involuntary muscle contractions.
Mechanism of Action
Competitive Antagonism: Atracurium competitively binds to nicotinic cholinergic receptors at the motor end-plate of skeletal muscles.
Blockade: By occupying these sites, it prevents the neurotransmitter acetylcholine from binding and triggering muscle contraction.
Reversal: The neuromuscular block can be reversed using acetylcholinesterase inhibitors like neostigmine, edrophonium, or pyridostigmine.
Pharmacokinetics :
Onset of Action: Muscle relaxation is typically achieved within 2 to 3 minutes of intravenous administration.
Duration: Provides intermediate-duration relaxation lasting roughly 20 to 35 minutes.
Metabolism: A unique feature of atracurium is its dual pathway of elimination. It is primarily degraded in the bloodstream via Hoffman elimination (a non-enzymatic, temperature- and pH-dependent breakdown) and by ester hydrolysis.
Organ Independence: Because of its metabolism, it is largely independent of liver and kidney function, making it a safer option for patients with organ impairment.
Half-life: The distribution phase is 2 to 3 minutes, with a terminal elimination half-life of about 20 minutes.
City Drug House Exporters provides:
Bulk supply for hospitals & distributors
Export to USA. Washington, INDIA
Regulatory documents (COA, MSDS, etc.)
Competitive pricing & reliable logistics
Contact for More Information :
📞 Contact City drug House Exporters from India
🌐 Websites:
https://www.citydrugexporters.com
📧 Email: citydrug123@gmail.com
📦 Business Type: Exporter | Bulk Supplier | Distributor
📲 WhatsApp: +91 9975390171
