Leading Afrezza Supplier from INDIA to Washington, USA | City Drug Exporters
City Drug Exporters supplies Afrezza from INDIA to Washington, USA. Trusted pharmaceutical exporter for wholesalers, distributors, pharmacies, and healthcare procurement companies
Afrezza is an ultra-rapid-acting, inhaled dry-powder formulation of recombinant human insulin. It is administered at the start of meals to manage post-meal blood sugar spikes. Afrezza achieves a peak insulin concentration in just 10-15 minutes and clears the body rapidly, mitigating late post-meal hypoglycemic events compared to injectable insulins.
Mechanism of Action :
Afrezza utilizes Technosphere delivery technology to pass human insulin into the blood.
Formulation: Human insulin is adsorbed onto microparticles of fumaryl diketopiperazine (FDKP).
Absorption: Particles deposit in the deep lung and dissolve at the physiologic pH of the alveolar surface.
Systemic Entry: Both insulin and the FDKP carrier are rapidly absorbed across the alveolar walls directly into the bloodstream.
Clearance: FDKP acts purely as an inactive excipient and is excreted unchanged in the urine.
Pharmacodynamics and Kinetics :
Afrezza acts significantly faster than rapid-acting injectable insulin analogs (lispro, aspart, glulisine).
Onset of Action: 12 to 15 minutes.
Peak Action: 45 to 53 minutes.
Duration of Activity: 160 to 180 minutes (about 2.5 to 3 hours).
Bioavailability: 21% to 30%.
Elimination Half-life: 28 to 39 minutes
Indications and Use :
Age Range: Indicated for pediatric (ages 6 and older) and adult patients with diabetes mellitus.
Diabetes Types: Used for both Type 1 and Type 2 diabetes.
Basal Requirement: For Type 1 diabetes, Afrezza must be combined with a long-acting (basal) insulin. It cannot be used as a standalone basal substitute.
Dosing Options: Available in single-dose cartridges of 4 units, 8 units, and 12 units.
City Drug House Exporters provides:
Bulk supply for hospitals & distributors
Export to USA. Washington, INDIA
Regulatory documents (COA, MSDS, etc.)
Competitive pricing & reliable logistics
Contact for More Information :
📞 Contact City drug House Exporters from India
🌐 Websites:
https://www.citydrugexporters.com
📧 Email: citydrug123@gmail.com
📦 Business Type: Exporter | Bulk Supplier | Distributor
📲 WhatsApp: +91 9975390171
City Drug Exporters supplies Afrezza from INDIA to Washington, USA. Trusted pharmaceutical exporter for wholesalers, distributors, pharmacies, and healthcare procurement companies
Afrezza is an ultra-rapid-acting, inhaled dry-powder formulation of recombinant human insulin. It is administered at the start of meals to manage post-meal blood sugar spikes. Afrezza achieves a peak insulin concentration in just 10-15 minutes and clears the body rapidly, mitigating late post-meal hypoglycemic events compared to injectable insulins.
Mechanism of Action :
Afrezza utilizes Technosphere delivery technology to pass human insulin into the blood.
Formulation: Human insulin is adsorbed onto microparticles of fumaryl diketopiperazine (FDKP).
Absorption: Particles deposit in the deep lung and dissolve at the physiologic pH of the alveolar surface.
Systemic Entry: Both insulin and the FDKP carrier are rapidly absorbed across the alveolar walls directly into the bloodstream.
Clearance: FDKP acts purely as an inactive excipient and is excreted unchanged in the urine.
Pharmacodynamics and Kinetics :
Afrezza acts significantly faster than rapid-acting injectable insulin analogs (lispro, aspart, glulisine).
Onset of Action: 12 to 15 minutes.
Peak Action: 45 to 53 minutes.
Duration of Activity: 160 to 180 minutes (about 2.5 to 3 hours).
Bioavailability: 21% to 30%.
Elimination Half-life: 28 to 39 minutes
Indications and Use :
Age Range: Indicated for pediatric (ages 6 and older) and adult patients with diabetes mellitus.
Diabetes Types: Used for both Type 1 and Type 2 diabetes.
Basal Requirement: For Type 1 diabetes, Afrezza must be combined with a long-acting (basal) insulin. It cannot be used as a standalone basal substitute.
Dosing Options: Available in single-dose cartridges of 4 units, 8 units, and 12 units.
City Drug House Exporters provides:
Bulk supply for hospitals & distributors
Export to USA. Washington, INDIA
Regulatory documents (COA, MSDS, etc.)
Competitive pricing & reliable logistics
Contact for More Information :
📞 Contact City drug House Exporters from India
🌐 Websites:
https://www.citydrugexporters.com
📧 Email: citydrug123@gmail.com
📦 Business Type: Exporter | Bulk Supplier | Distributor
📲 WhatsApp: +91 9975390171
Keywords
