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Exporter India Abalam Tablet| Bulk Supply HIV AIDS Medicines.
Buy Exporter India Abalam Tablet in bulk from India. Leading HIV AIDS Medicines export City Drug House Exporters offering global supply with latest regulatory updates and competitive pricing.
Abalam Tablet is a fixed-dose combination antiretroviral medication containing Abacavir (600 mg) and Lamivudine (300 mg), used to treat HIV-1 infection. As a Nucleoside Reverse Transcriptase Inhibitor (NRTI), it inhibits HIV-1 and HIV-2 replication, reducing viral load and increasing CD4 cell counts, usually as part of combination therapy (HAART).
Pharmacology and Mechanism of Action
Abalam contains two active ingredients that work by disrupting the reverse transcriptase enzyme necessary for HIV reproduction:
Abacavir: A synthetic carbocyclic nucleoside analogue. It is converted intracellularly to its active metabolite, carbovir triphosphate (CBV-TP). It acts by inhibiting HIV-1 reverse transcriptase and terminating the viral DNA chain.
Lamivudine: A dideoxynucleoside cytosine analog. It is phosphorylated intracellularly to lamivudine triphosphate (3TC-TP), which acts as a competitor to natural substrate and causes DNA chain termination, halting viral DNA synthesis.
Key Details :
Indication: Treatment of HIV-1 infection in adults and adolescents, usually combined with other antiretroviral agents.
Dosage: Typically taken once daily with or without food.
Common Side Effects: Insomnia, headache, fatigue, dizziness, nausea, diarrhea, rash, and anorexia.
Precautions: Requires screening for the HLA-B*5701 allele due to risk of hypersensitivity reactions to Abacavir. Not recommended for patients with kidney failure.
Warning: Do not stop taking this medication abruptly, as this may lead to treatment failure or worsening of hepatitis, especially if the patient is co-infected.
City Drug House Exporters provides:
Bulk supply for hospitals & distributors
Export to USA , Washington, INDIA
Regulatory documents (COA, MSDS, etc.)
Competitive pricing & reliable logistics
Contact for More Information :
📞 Contact City drug House Exporters from India
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